how long does maxalt stay in your system


Food has no significant effect on the bioavailability of rizatriptan but delays the time to reach peak concentration by an hour. Not all possible interactions are listed in this medication guide.Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Maxalt only for the indication prescribed.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Copyright 1996-2020 Cerner Multum, Inc. Placental transfer of drug to the fetus was demonstrated in both species.Oral administration of rizatriptan (0, 2, 10, or 100 mg/kg/day) to female rats prior to and during mating and continuing throughout gestation and lactation resulted in reduced body weight in offspring from birth and throughout lactation at all but the lowest dose tested (2 mg/kg/day).

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Maxalt (rizatriptan) is a headache medicine that narrows the blood vessels around the brain. Plasma exposure at the no-effect dose (10 mg/kg/day) for reproductive toxicity was approximately 15 times that in humans at the MRHD.Oral administration of rizatriptan (0, 5, 35, or 250 mg/kg/day) to male rats prior to and during mating resulted in no impairment of fertility or reproductive performance. These sensations do not usually last for long, but if they continue or become intense, do not take any more tablets, and let your doctor know as soon as possible.Rizatriptan can make you feel sleepy. Orally disintegrating tablets are packaged in a blister within an outer aluminum pouch and patients should not remove the blister from the outer pouch until just prior to dosing.

The treatment phase of the study had two stages. Tell your doctor if you are breast-feeding a baby.Maxalt is not FDA-approved for use by anyone younger than 6 years old.Take Maxalt exactly as prescribed by your doctor.

Adverse reaction frequencies were also unchanged by concomitant use of drugs commonly taken for migraine prophylaxis (including propranolol), oral contraceptives, or analgesics. The recommended dose of MAXALT is 5 mg in patients weighing less than 40 kg (88 lb), and 10 mg in patients weighing 40 kg (88 lb) or more.The efficacy and safety of treatment with more than one dose of MAXALT within 24 hours in pediatric patients 6 to 17 years of age have not been established.For MAXALT-MLT Orally Disintegrating Tablets, administration with liquid is not necessary.

pediatric patients is expected to be similar to that in adults.Clinical studies of MAXALT did not include sufficient numbers of subjects aged 65 and over to
The 10-mg dose may provide a greater effect than the 5-mg dose, but may have a greater risk of adverse reactions [see Although the effectiveness of a second dose or subsequent doses has not been established in placebo-controlled trials, if the migraine headache returns, a second dose may be administered 2 hours after the first dose.

Other reported clinical experience has

In a drug interaction study, when MAXALT 10 mg was administered to subjects (n=12) receiving concomitant therapy with the selective, reversible MAO-A inhibitor, moclobemide 150 mg t.i.d., there were mean increases in rizatriptan AUC and Cmax of 119% and 41% respectively; and the AUC of the active N-monodesmethyl metabolite of rizatriptan was increased more than 400%. A dangerous drug interaction could occur. Here's How Long Various Drugs Stay in Your Body.

Plasma concentrations of rizatriptan may be increased by drugs that are selective MAO-A inhibitors (e.g., moclobemide) or nonselective MAO inhibitors [type A and B] (e.g., isocarboxazid, phenelzine, tranylcypromine, and pargyline). Version: 11.01.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Because studies are conducted at different times, with different samples of patients, by different investigators, employing different criteria and/or different interpretations of the same criteria, under different conditions (dose, dosing regimen, etc.

The percentage of patients achieving the primary efficacy endpoint of no headache pain at 2 hours after treatment was significantly greater in patients who received MAXALT-MLT, compared with those who received placebo (33% vs. 24%). Do not take more than 30 mg of rizatriptan in 24 hours.

Each lyophilized orally disintegrating tablet contains the following inactive ingredients: gelatin, mannitol, The recommended starting dose of MAXALT is either 5 mg or 10 mg for the acute treatment of migraines in adults. Tramadol. The safety of treating, on average, more than four headaches in a 30-day period has not been established.Dosing in pediatric patients is based on the patient's body weight.

After taking a Maxalt tablet, you must wait two (2) hours before taking a second tablet. If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side … Copyright © Vitals Consumer Services LLC

Never give it to other people even if their condition appears to be the same as yours.If you are having an operation or any dental treatment, tell the person carrying out the treatment which medicines you are taking.Do not keep out-of-date or unwanted medicines. If you would like more information, talk to your doctor.

Because the reports include events observed in open studies, the role of MAXALT in their causation cannot be reliably determined.